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The result is a direct increase in causation of various CVDs including: Atherosclerosis Hypertension Type-2 diabetes mellitus Heart Attacks or Ischemic events Heart failure Arrythmias Stroke Peripheral Artery Disease Abdominal aortic aneurysm Venous and Pulmonary embolism Consequences of tobacco use Cigarettes and smokeless tobacco contain numerous chemical toxins which can damage functioning of various pathways